Description
This project will investigate the role and mechanism of the micro-RNA processing complex (SRSF3 OncomiR-1) in colorectal cancer. Experiemntal approaches will include biochemical, biophysical and structural biology methods to understand how SRSF3 interacts with Drosha and DGCR8 to process the OncomiR-1 RNA substrate. The outcome of this project will provide insights into how SRSF3-OncomiR1 complex contribute to the progression of colorectal cancer.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
Cancer, biochemistry, structural biology
School
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research
Available options
PhD/Doctorate
Masters by research
Honours
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Monash Health Translation Precinct (Monash Medical Centre)
Co-supervisors
Dr
Minna-Liisa Anko
(External)