Description
Our laboratory aims to create new knowledge in host-pathogen interactions driven by intracellular bacterial pathogens. Our research team has projects investigating Coxiella burnetii, Legionella species and Salmonella enterica. We are fascinated by Coxiella burnetii, the causative agent of Q fever, and Legionella species, the causative agents of Legionnaires' disease, which replicate inside human cells in a manner that requires the Dot/Icm type IV secretion system. This multi-protein apparatus delivers a huge number of novel effector proteins into human host cells, manipulating many aspects of human cell biology, to facilitate intracellular replication of the pathogen. However, very little is known about how individual effectors influence pathogen success.
Our team employs a range of innovative and multi-disciplinary approaches to investigate the important functions of these novel bacterial effector proteins.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
Intracellular bacterial pathogens, effector proteins, secretion system, host-pathogen interactions, microbiology, bacterial pathogenesis
School
Biomedicine Discovery Institute (School of Biomedical Sciences) » Microbiology
Available options
PhD/Doctorate
Honours
BMedSc(Hons)
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Biomedicine Discovery Institute