Description
This project will structurally and functionally characterise the S-Pumps found in Clostridioides difficile, Bacillus solimangrovi, and Paenibacillus polymyxa. S-Pumps are a novel secretion system likely embedded within the surface layer (S-layer) of Gram-positive bacteria in order to secrete toxins and/or remove antimicrobial agents that were intended to kill them.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
cryoEM; cryoET; S-layer; secretion system; Gram-positive bacteria; MIC; super-resolution microscopy; protein assembly
School
Biomedicine Discovery Institute (School of Biomedical Sciences) » Microbiology
Available options
PhD/Doctorate
Honours
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Monash Clayton Campus
Co-supervisors
Prof
Trevor Lithgow