Description
Fibroblasts in the lymph nodes are able to regulate differentiation and localization of innate and adaptive immune cells. They are also a primary source of CXCL12 that has been recently shown to regulate NK cell localization is lymph nodes via the CXCL12/CXCR4 axis. The project aims to investigate the effect of fibroblasts in NK cell activation in lymph nodes and investigate the effect such regulation might have on cancer metastasis.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
Department of Biochemistry and Molecular Biology, fibroblasts, RNA-seq, Innate immunity, NK cells
School
Biomedicine Discovery Institute (School of Biomedical Sciences)
Available options
PhD/Doctorate
Masters by research
Honours
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
15 Innovation Walk
Research webpage
Co-supervisors
Dr
Anne Fletcher