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Oligodendroglial dynamics in ageing and disease

Description 
Oligodendrocytes play a vital role as supporting cells within the central nervous system, aiding in signal transmission among a plethora of other functions. They produce a specialised lipid sheath known as 'myelin,' which envelops axons of neurons, facilitating rapid signal conduction. Unfortunately, myelin sheaths are susceptible to damage in various neurological diseases, including multiple sclerosis. Our project focuses on investigating the mechanisms through which oligodendrocytes contribute to myelin regeneration in diseased conditions, while also exploring how the process of myelination is influenced by ageing.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Oligodendrocytes; Glia; Neuroscience; Plasticity; Multiple Sclerosis; Myelin, Demyelination; Remyelination
School 
Biomedicine Discovery Institute (School of Biomedical Sciences) » Anatomy and Developmental Biology
Available options 
PhD/Doctorate
Masters by research
Masters by coursework
Honours
BMedSc(Hons)
Time commitment 
Full-time
Part-time
Top-up scholarship funding available 
No
Physical location 
15 Innovation Walk
Co-supervisors 
Dr 
David Gonsalvez

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