Predictors of diabetic neuropathy among patients with type 2 diabetes mellitus; a matched case control study

Diabetes mellitus is a global public health concern that places a great burden on individuals’ health and the healthcare system alike. The prevalence of diabetes complications is also alarmingly high, which can be microvascular (e.g., neuropathy, retinopathy, and nephropathy) and macrovascular (e.g., coronary artery disease, peripheral artery disease, and cerebrovascular disease). The increasing burden of diabetes mellitus and its complications has led to a drastic 316% increase in global health spending on diabetes over the past fifteen years. Diabetic neuropathy is one of the most common among all diabetes complications, affecting nearly 50% of the diabetic population at some point in their lifetime and leads to the highest hospitalization rate among all diabetes complications combined. DPN worsens the burden of diabetes substantially, contributing to reduced quality of life and increasing the risk of foot ulcers, infections, amputation, and disability. Individuals with painful neuropathy are known to be at higher risk of developing mental disorders, including depression, anxiety, and sleep disturbance. The nerve damage induced by neuropathy is usually irreversible, highlighting the necessity for risk factor prevention and early detection to mitigate its devastating consequences. This matched case control study examines the possible risk factors among patients with T2DM in Arab population, which is a population known for its high diabetes prevalence. The data collection completed in June 2024. Data is awaiting statistical analysis