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Germinal centre organoids to investigate human immune response to infection and vaccination
Antibody development in response to infection and vaccination in humans is poorly understood, in part due to the difficult in accessing secondary...
Supervisor: A/Prof Michelle Boyle
Host directed therapy to boost protective immunity to malaria.
Immunity to malaria is slow to develop due to the rapid induction of regulatory cell responses that hamper adaptive immunity. Type I IFN signalling...
Supervisor: A/Prof Michelle Boyle
Impact of malaria and other host factors on covid immune responses following infection and vaccination.
Despite initial fears, the SARS-CoV-2 pandemics impact in sub-Sahara Africa has been less serious than anticipated. Possible reasons for this...
Supervisor: A/Prof Michelle Boyle
Malaria immune development in spleen germinal centres in human infection
Protective immunity to malaria is mediated by antibodies that block parasite growth. Antibody development occurs within the germinal centres, and...
Supervisor: A/Prof Michelle Boyle
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